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The computer simulation of the distribution of biologically active fragments and bonds which are predicted to be susceptible to the action of endopeptidases of known specificity, hydropathy index and prediction of secondary structures were performed. The average values of hydropathy index calculated for bioactive fragments of selected animal proteins predicted in silico to be released by proteolytic...
Proteins, apart from their basic functions, may play the role of precursors of the peptides that regulate the body functions and/or show antihypertensive, antithrombotic, antiamnestic, immunomodulating and other activities. Computer analysis of 109 protein sequences, done with help of a database containing 109 protein sequences and 1100 bioactive peptides sequences, has been presented. Following discriminants...
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