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Hintergrund Unter dem Abscopal-Effekt versteht man die Reduktion von Metastasen außerhalb des Bestrahlungsareales nach lokaler Bestrahlung. Fallbeschreibung Der vorliegende Fall eines Patienten mit metastasiertem Melanom beschreibt die sequenzielle Gabe von Temozolomid und Ipilimumab plus Radiotherapie. Das applizierte Therapieschema wurde vom Patienten gut vertragen. Es konnte unter dieser Therapie...
Summary Adjuvant chemotherapy for grade 2 and 3 soft tissue sarcoma (STS) patients still has to be considered experimental. Fifty-nine patients underwent primary surgery by wide or marginal excision and were subsequently randomized to receive radiotherapy alone or in combination with six courses of chemotherapy consisting of ifosfamide, DTIC, and doxorubicin administered in 14-day intervals supported...
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