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Microsized cellular constructs such as cellular aggregates and cell-laden hydrogel blocks are attractive cellular building blocks to reconstruct 3D macroscopic tissues with spatially ordered cells in bottom-up tissue engineering. In this regard, microfluidic techniques are remarkable methods to form microsized cellular constructs with high production rate and control of their shapes such as point,...
In this presentation, I will talk about the recent activity of our group to fabricate thick, highly-dense, heterogeneous 3D tissue structures using MEMS/Microfluidic technology. We prepare cell-laden micro beads, micro fibers and micro plates as building blocks for the 3D construction; the 3D cellular structures can be formed by molding, weaving, and folding of each block. These techniques will be...
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