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Potential technological applications for artificial lipid and proteo-lipid membranes, such as capsules for controlled delivery of drugs and coatings for biosensors and biomaterials, are in many cases limited by the inherent instability of lipid lamellar phases. Development of methods to stabilize artificial lipid membranes has therefore been a focus of research efforts since the 1970s. Linear and...
Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (MS) coupled with affinity capture is a well-established method to extract biological analytes from complex samples followed by label-free detection and identification. Many bioanalytes of interest bind to membrane-associated receptors; however, the matrices and high-vacuum conditions inherent to MALDI-TOF MS...
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