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Lipid hydroperoxides (LOOHs), including cholesterol‐ and phospholipid‐derived species, are reactive intermediates that arise during photosensitized peroxidation of unsaturated lipids in biological membranes. These intermediates may appear in cancer cell membranes during anti‐tumor photodynamic therapy (PDT). Photodynamically generated LOOHs have several different fates, including (a) iron‐catalyzed...