Search results for: Lei Tang

Items from 1 to 20 out of 592 results

article

Targeting the Labile Iron Pool with Engineered DFO Nanosheets to Inhibit Ferroptosis for Parkinson's Disease Therapy

Li Lei, Jiali Yuan, Zhijun Dai, Song Xiang, more

Advanced Materials > 36 > 41 > n/a - n/a

Ferroptosis in neurons is considered one of the key factors that induces Parkinson's disease (PD), which is caused by excessive iron accumulation in the intracellular labile iron pool (LIP). The iron ions released from the LIP lead to the aberrant generation of reactive oxygen species (ROS) to trigger ferroptosis and exacerbate PD progression. Herein, a pioneering design of multifunctional nanoregulator...

article

Room‐Temperature Out‐of‐Plane Ferroelectricity and Resistance Switching Based on 2D Bi₂O₂Se

Lei Tang, Le‐Yang Dang, Mengjiao Han, Shengnan Li, more

Advanced Functional Materials > 34 > 40 > n/a - n/a

Although 2D Bi₂O₂Se plays an important role in the electronics and optoelectronics based on its in‐plane property, its out‐of‐plane electrical transport behavior remains unclear, especially in fabricating vertical devices with high integration density for novel functionality. Here, a solution‐processed method is developed to prepare 2D Bi₂O₂Se with mass production (e.g., hundreds of milliliter scale)...

article

Frontispiece: Divergent Synthesis of Sulfur‐Containing Bridged Cyclobutanes by Lewis Acid Catalyzed Formal Cycloadditions of Pyridinium 1,4‐Zwitterionic Thiolates and Bicyclobutanes

Yuanjiu Xiao, Feng Wu, Lei Tang, Xu Zhang, more

Angewandte Chemie International Edition > 63 > 40 > n/a - n/a

Cycloadditions. Bicyclo[n.1.1]alkanes show great promise in substituting planar aromatic rings, akin to the "butterfly effect". In their Research Article (e202408578), Jian‐Jun Feng et al. present a Lewis acid‐catalyzed cycloaddition of bicyclobutanes (butterfly conformation) with 2D pyridinium thiolate derivatives.

article

Divergent Synthesis of Sulfur‐Containing Bridged Cyclobutanes by Lewis Acid Catalyzed Formal Cycloadditions of Pyridinium 1,4‐Zwitterionic Thiolates and Bicyclobutanes

Yuanjiu Xiao, Feng Wu, Lei Tang, Xu Zhang, more

Angewandte Chemie International Edition > 63 > 40 > n/a - n/a

Bridged cyclobutanes and sulfur heterocycles are currently under intense investigation as building blocks for pharmaceutical drug design. Two formal cycloaddition modes involving bicyclobutanes (BCBs) and pyridinium 1,4‐zwitterionic thiolate derivatives were described to rapidly expand the chemical space of sulfur‐containing bridged cyclobutanes. By using Ni(ClO₄)₂ as the catalyst, an uncommon higher‐order...

article

Frontispiz: Divergent Synthesis of Sulfur‐Containing Bridged Cyclobutanes by Lewis Acid Catalyzed Formal Cycloadditions of Pyridinium 1,4‐Zwitterionic Thiolates and Bicyclobutanes

Yuanjiu Xiao, Feng Wu, Lei Tang, Xu Zhang, more

Angewandte Chemie > 136 > 40 > n/a - n/a

article

Divergent Synthesis of Sulfur‐Containing Bridged Cyclobutanes by Lewis Acid Catalyzed Formal Cycloadditions of Pyridinium 1,4‐Zwitterionic Thiolates and Bicyclobutanes

Yuanjiu Xiao, Feng Wu, Lei Tang, Xu Zhang, more

Angewandte Chemie > 136 > 40 > n/a - n/a

article

Bioinspired Slippery Surfaces for Liquid Manipulation from Tiny Droplet to Bulk Fluid

Gang Wang, Fuliang Ma, Lijing Zhu, Ping Zhu, more

Advanced Materials > 36 > 37 > n/a - n/a

Slippery surfaces, which originate in nature with special wettability, have attracted considerable attention in both fundamental research and practical applications in a variety of fields due to their unique characteristics of superlow liquid friction and adhesion. Although research on bioinspired slippery surfaces is still in its infancy, it is a rapidly growing and enormously promising field. Herein,...

article

Frustrated Lewis Pairs on Zr Single Atoms Supported N‐Doped TiO_2‐x Catalysts for Electrochemical Nitrate Reduction To Ammonia

Lekuan Yang, Chaochen Wang, Yufeng Li, Wangxin Ge, more

Advanced Functional Materials > 34 > 36 > n/a - n/a

The electrochemical reduction of nitrates (NO₃RR) for ammonia synthesis at room temperature holds immense potential. One key challenge is the adsorption and activation of NO₃⁻, along with the provision of sufficient active hydrogen to accelerate the hydrogenation process. Here, the study prepares N‐doped TiO_2‐x supported by Zr single atoms (Zr‐TiON) with rich oxygen vacancies (O_v), in which unsaturated...

article

Improved Tensile Strength and SCC Resistance via Nonisothermal Creep Aging under a High Stress Level

Zhihao Yi, Guofu Xu, Lei Tang, Zhihao Zhao, more

Advanced Engineering Materials > 26 > 15 > n/a - n/a

Compared with conventional isothermal creep aging (ICA), non‐ICA (NICA) does not involve a prolonged holding stage, but only has heating and cooling stages. During the NICA process, the precipitates nucleate and grow up in the early part of heating stage, resulting in fluctuations in creep rate and an increase in strength. The coarsening of precipitates in the later part of the heating stage can lead...

article

Switching between the [2π+2σ] and Hetero‐[4π+2σ] Cycloaddition Reactivity of Bicyclobutanes with Lewis Acid Catalysts Enables the Synthesis of Spirocycles and Bridged Heterocycles

Ji‐Jie Wang, Lei Tang, Yuanjiu Xiao, Wen‐Biao Wu, more

Angewandte Chemie International Edition > 63 > 29 > n/a - n/a

The exploration of the complex chemical diversity of bicyclo[n.1.1]alkanes and their use as benzene bioisosteres has garnered significant attention over the past two decades. Regiodivergent syntheses of thiabicyclo[4.1.1]octanes (S‐BCOs) and highly substituted bicyclo[2.1.1]hexanes (BCHs) using a Lewis acid‐catalyzed formal cycloaddition of bicyclobutanes (BCBs) and 3‐benzylideneindoline‐2‐thione...

article

Switching between the [2π+2σ] and Hetero‐[4π+2σ] Cycloaddition Reactivity of Bicyclobutanes with Lewis Acid Catalysts Enables the Synthesis of Spirocycles and Bridged Heterocycles

Ji‐Jie Wang, Lei Tang, Yuanjiu Xiao, Wen‐Biao Wu, more

Angewandte Chemie > 136 > 29 > n/a - n/a

article

The Robust Ferroelectric and Electrical Response in 2D Bi₂O₂Se Semiconductor

Usman Khan, Runzhang Xu, Adeela Nairan, Mengjiao Han, more

Advanced Functional Materials > 34 > 27 > n/a - n/a

The amelioration of atomically thin ferroelectric materials is imperative for next‐generation outperformed two‐dimensional (2D) electronics, which is elusive by their bulk counterparts. These remarkable materials’ ferroelectric and piezoelectric features are the fundamental urges in optoelectronics, electronics, and energy harvesting. In this work, 2D ferroelectric Bi₂O₂Se flakes have been synthesized...

article

Discovery of Novel Hybrids of Edaravone and 6‐Phenyl‐4,5‐dihydropyridazin‐3(2H)‐one with Antiplatelet Aggregation and Neuroprotection for Ischemic Stroke Treatment

Yi Li, Jieying He, Bilan Luo, Qinyang Yu, more

Chemistry & Biodiversity > 21 > 5 > n/a - n/a

Drugs with anti‐platelet aggregation and neuroprotection are of great significance for the treatment of ischemic stroke. A series of edaravone and 6‐phenyl‐4,5‐dihydropyridazin‐3(2H)‐one hybrids were designed and synthesized. Among them, 6g showed the most effective cytoprotective effect against oxygen‐glucose deprivation/reoxygenation‐induced damage in BV2 cells and an excellent inhibitory effect...

article

Effect of the Heating/Cooling Rate of Nonisothermal Aging on Microstructure and Mechanical Properties of 2050 Al–Li Alloy

Guofu Xu, Yuan Tang, Yao Li, Zhihao Yi, more

Advanced Engineering Materials > 26 > 9 > n/a - n/a

The effect of the heating/cooling rates of nonisothermal aging (NIA) on microstructure and mechanical properties of 2050 Al–Li alloy are investigated. The 2050 Al–Li alloy is first solid solutioned and predeformed and then heated from 130 to 220 °C at different rates of 20, 30 °C h⁻¹, or 40 °C h⁻¹ and then cooled to 150 °C. The results show that the mechanical properties of the alloy subjected to...

article

High‐temperature resistant copolymer oil well cement retarder: Synthesis, assessment of performance, and mechanism of retardation

Jifa Bian, Zhongbin Ye, Xuecheng Zheng, Chengwen Deng, more

Journal of Applied Polymer Science > 141 > 18 > n/a - n/a

This work used aqueous solution free radical polymerization to create polymers of 2‐acrylamide‐2‐methylpropane sulfonic acid, itaconic acid, and allyl polyoxyethylene ether as a high‐temperature resistant retarder (APMS/IA/APEG, from now on referred to as AIA). Gel permeation chromatography, fourier transform infrared (FTIR), proton nuclear magnetic resonance (¹HNMR), and thermo‐gravimetric analysis...

article

Design and Synthesis of Novel Phthalide Derivatives containing 1,3,4‐Oxadiazole/1,2,4‐Triazole Units as Potential Antifungal Agents

Yong Li, Zhongfu Luo, Wenjing Liu, Wenzhang Chen, more

Chemistry & Biodiversity > 21 > 3 > n/a - n/a

Four series of novel 1,3,4‐oxadiazole/1,2,4‐triazole hybrids of phthalide derivatives were designed and synthesized to search for novel potential antifungal agents. Preliminary antifungal activity assay results showed that compounds 4 a, 4 b, 4 m, 5 b, 5 f, 5 h, and 7 h exhibited moderate to excellent inhibitory activity against some phytopathogenic fungi. Among them, compound 5 b displayed the most...

article

Organo‐Catalyzed Intermolecular Dehydrative Coupling Reaction to Prepare Arylacetic Acid Derivatives

Fei Chen, Huidan Geng, Yonglong Zhao, Chun Li, more

Advanced Synthesis & Catalysis > 366 > 3 > 502 - 507

Herein, the use of triphenylmethylium tetrakis(pentafluorophenyl)borate as an efficient catalyst for the intermolecular dehydrative coupling of p‐hydroxymandelic acid hydrate with substituted aromatic amines and (thio)phenols was developed, which allows for the preparation of arylacetic acid derivatives in a convenient manner. Notably, this method offers several advantages, including being prefunctionalization...

article

Trends in photodynamic therapy for dermatology in recent 20 years: A scientometric review based on CiteSpace

Fujun Huang, Qiang Fu, Lei Tang, Mingdan Zhao, more

Journal of Cosmetic Dermatology > 23 > 2 > 391 - 402

Objective Analyze the research state and development trend of photodynamic therapy for dermatology using visual knowledge graphs derived from the Web of Science Core Collection database. Methods The Web of Science Core Collection database was utilized as the search data source for the bibliometric analysis, and the associated articles published between January 1, 2000, and December 31, 2022, were...

article

Establishment of temperature‐strength response prediction model of supramolecular gel temporary plugging agent by response surface method analysis

Nanjun Lai, Yongqiang Tian, Junqi Wang, Hongwei Xu, more

Journal of Applied Polymer Science > 141 > 9 > n/a - n/a

In this study, response surface methodology (RSM) was applied to optimize the preparation of a supramolecular gel temporary plugging agent. According to single‐factor experiments, results showed that the gelling temperature was preset at 100°C, and the gelling strength reached the maximum. Three‐factor RSM model prediction was carried out to explore the determination coefficient (R²) of the gelling...

article

Silver‐Catalyzed Dearomative [2π+2σ] Cycloadditions of Indoles with Bicyclobutanes: Access to Indoline Fused Bicyclo[2.1.1]hexanes**

Lei Tang, Yuanjiu Xiao, Feng Wu, Jin‐Lan Zhou, more

Angewandte Chemie International Edition > 62 > 48 > n/a - n/a

Bicyclo[2.1.1]hexanes (BCHs) are becoming ever more important in drug design and development as bridged scaffolds that provide underexplored chemical space, but are difficult to access. Here a silver‐catalyzed dearomative [2π+2σ] cycloaddition strategy for the synthesis of indoline fused BCHs from N‐unprotected indoles and bicyclobutane precursors is described. The strain‐release dearomative cycloaddition...

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INFONA - science communication portal

Search results for: Lei Tang

Targeting the Labile Iron Pool with Engineered DFO Nanosheets to Inhibit Ferroptosis for Parkinson's Disease Therapy

Room‐Temperature Out‐of‐Plane Ferroelectricity and Resistance Switching Based on 2D Bi₂O₂Se

Frontispiece: Divergent Synthesis of Sulfur‐Containing Bridged Cyclobutanes by Lewis Acid Catalyzed Formal Cycloadditions of Pyridinium 1,4‐Zwitterionic Thiolates and Bicyclobutanes

Divergent Synthesis of Sulfur‐Containing Bridged Cyclobutanes by Lewis Acid Catalyzed Formal Cycloadditions of Pyridinium 1,4‐Zwitterionic Thiolates and Bicyclobutanes

Frontispiz: Divergent Synthesis of Sulfur‐Containing Bridged Cyclobutanes by Lewis Acid Catalyzed Formal Cycloadditions of Pyridinium 1,4‐Zwitterionic Thiolates and Bicyclobutanes

Divergent Synthesis of Sulfur‐Containing Bridged Cyclobutanes by Lewis Acid Catalyzed Formal Cycloadditions of Pyridinium 1,4‐Zwitterionic Thiolates and Bicyclobutanes

Bioinspired Slippery Surfaces for Liquid Manipulation from Tiny Droplet to Bulk Fluid

Frustrated Lewis Pairs on Zr Single Atoms Supported N‐Doped TiO_2‐x Catalysts for Electrochemical Nitrate Reduction To Ammonia

Improved Tensile Strength and SCC Resistance via Nonisothermal Creep Aging under a High Stress Level

Switching between the [2π+2σ] and Hetero‐[4π+2σ] Cycloaddition Reactivity of Bicyclobutanes with Lewis Acid Catalysts Enables the Synthesis of Spirocycles and Bridged Heterocycles

Switching between the [2π+2σ] and Hetero‐[4π+2σ] Cycloaddition Reactivity of Bicyclobutanes with Lewis Acid Catalysts Enables the Synthesis of Spirocycles and Bridged Heterocycles

The Robust Ferroelectric and Electrical Response in 2D Bi₂O₂Se Semiconductor

Discovery of Novel Hybrids of Edaravone and 6‐Phenyl‐4,5‐dihydropyridazin‐3(2H)‐one with Antiplatelet Aggregation and Neuroprotection for Ischemic Stroke Treatment

Effect of the Heating/Cooling Rate of Nonisothermal Aging on Microstructure and Mechanical Properties of 2050 Al–Li Alloy

High‐temperature resistant copolymer oil well cement retarder: Synthesis, assessment of performance, and mechanism of retardation

Design and Synthesis of Novel Phthalide Derivatives containing 1,3,4‐Oxadiazole/1,2,4‐Triazole Units as Potential Antifungal Agents

Organo‐Catalyzed Intermolecular Dehydrative Coupling Reaction to Prepare Arylacetic Acid Derivatives

Trends in photodynamic therapy for dermatology in recent 20 years: A scientometric review based on CiteSpace

Establishment of temperature‐strength response prediction model of supramolecular gel temporary plugging agent by response surface method analysis

Silver‐Catalyzed Dearomative [2π+2σ] Cycloadditions of Indoles with Bicyclobutanes: Access to Indoline Fused Bicyclo[2.1.1]hexanes**

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