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As a promising technology for the future Internet, network virtualization makes it possible to reshape currently ossified network architecture. This paper proposes a limited scale-free model for construction of virtual networks topologies, aiming to reduce network average path length and achieve a simplified virtual network. In the progress of constructing, new links are added into the initial network...
Trastuzumab is effective in the treatment of HER2/neu over-expressing breast cancer, but not all patients benefit from it. In vitro data suggest a role for HER3 in the initiation of signaling activity involving the AKT–mTOR pathway leading to trastuzumab insensitivity. We sought to investigate the potential of HER3 alone and in the context of p95HER2 (p95), a trastuzumab resistance marker, as biomarkers...
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