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We report here an in vitro evaluation of silica nanoparticle uptake by lung epithelial cells (A549), the cytotoxic effect of the particles and we propose autophagy as possible survival strategy. The effect of surface charge, serum proteins and the influence of inhibitors on the uptake of 20nm monodispersed nanoparticles with various functional groups are discussed. Uptake rate of the particles with...
Gold nanoparticles (AuNPs) are currently used in several fields including biomedical applications, although no conclusive information on their cytotoxicity is available. For this reason this work has investigated the effects of AuNPs in vitro on Balb/3T3 mouse fibroblasts. Results obtained exposing cells for 72h to AuNPs 5 and 15nm citrate stabilized, revealed cytotoxic effects only for AuNPs 5nm...
In this paper, we report a novel, efficient and versatile process to produce high concentrations of silver nanoprisms, while controlling their size (prism height) and size dispersity, using a “modified polyol process” (microwave-assisted process). If the formation of silver spherical particles, nanocubes or nanowires has already been reported using the classical polyol process (reduction of AgNO ...
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