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For improved physical stability and fast accumulation in sentinel lymph nodes in vivo, indocyanine green (ICG) was incorporated into exosomes (EXOs) to form a novel ICG-based near-infrared fluorescence probe. Compared with free ICG, prepared ICG-TBAI-encapsulated EXOs (ICG/EXOs) smaller than 50 nm had greater physicochemical stability in aqueous solution when exposed to light at 37 °C. In addition,...
A hyaluronidase (HAdase) has been noticed as a potential drug target as well as prognostic marker because of its close associations with tumor invasion, metastasis, and angiogenesis. Accordingly, precise monitoring of HAdase activity in vivo seems to be crucial not only for the evaluation of HAdase activity but also for non‐invasive molecular imaging. In our study, we propose a new organic, near‐infrared...
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