Search results for: Karl Maurer

Items from 1 to 20 out of 23 results

chapter

New Approaches to the Synthesis of Addressable Microarray Molecular Libraries

Karl Maurer, Kevin D. Moeller

Integrated Analytical Systems > Microarrays > Applications > 227-246

Approaches for the synthesis of molecular libraries on addressable arrays of microelectrodes are presented. In each case, substrates are fixed to a polymer coating of the array in the regions proximal to the microelectrodes. Selected micro-electrodes are then used to synthesize chemical reagents that initiate reactions involving the substrates. The reagents generated at the electrodes are confined...

article

Microelectrode array biosensor for studying carbohydrate-mediated interactions

Jeffrey W. Chamberlain, Karl Maurer, John Cooper, Wanda J. Lyon, more

Biosensors and Bioelectronics > 2012 > 34 > 1 > 253-260

Carbohydrate-mediated host-pathogen interactions are essential to bacterial and viral pathogenesis, and represent an attractive target for the development of antiadhesives to prevent infection. We present a versatile microelectrode array-based platform to investigate carbohydrate-mediated protein and bacterial binding, with the objective of developing a generalizable method for screening inhibitors...

article

Site-Selective, Cleavable Linkers: Quality Control and the Characterization of Small Molecules on Microelectrode Arrays

Bo Bi, Richard Y.-C. Huang, Karl Maurer, Ceng Chen, more

The Journal of Organic Chemistry > 2011 > 76 > 21 > 9053 - 9059

article

Site-Selectively Functionalizing Microelectrode Arrays: The Use of Cu(I)-Catalysts

Jennifer Bartels, Peng Lu, Karl Maurer, Amy V. Walker, more

Langmuir > 2011 > 27 > 17 > 11199 - 11205

article

Building Addressable Libraries: The Use of “Safety-Catch” Linkers on Microelectrode Arrays

Bo Bi, Karl Maurer, Kevin D. Moeller

Journal of the American Chemical Society > 2010 > 132 > 49 > 17405 - 17407

article

Building Addressable Libraries: Site-Selective Use of Pd(0) Catalysts on Microelectrode Arrays

Libo Hu, Melissae Stuart, Jun Tian, Karl Maurer, more

Journal of the American Chemical Society > 2010 > 132 > 46 > 16610 - 16616

article

A New Porous Reaction Layer for Developing Addressable Molecular Libraries

Libo Hu, Jennifer L. Bartels, Jeremy W. Bartels, Karl Maurer, more

Journal of the American Chemical Society > 2009 > 131 > 46 > 16638 - 16639

article

Building Addressable Libraries: Site-Selective Suzuki Reactions on Microelectrode Arrays

Libo Hu, Karl Maurer, Kevin D. Moeller

Organic Letters > 2009 > 11 > 6 > 1273 - 1276

article

Building addressable libraries: a site-selective allyl alkylation reaction

Jun Tian, Karl Maurer, Kevin D. Moeller

Tetrahedron Letters > 2008 > 49 > 39 > 5664-5667

A Pd(0) catalyst has been used to effect allyl alkylation reactions at pre-selected locations on an addressable microelectrode array. The reactions provide a new approach to site-selective carbon–carbon bond formation and a new method for placing substrates on the surface of a microelectrode array.

article

Moving Known Libraries to an Addressable Array: A Site-Selective Hetero-Michael Reaction

Melissae Stuart, Karl Maurer, Kevin D. Moeller

Bioconjugate Chemistry > 2008 > 19 > 8 > 1514 - 1517

article

Microelectrode Arrays and Ceric Ammonium Nitrate: A Simple Strategy for Developing New Site-Selective Synthetic Methods

David Kesselring, Karl Maurer, Kevin D. Moeller

Journal of the American Chemical Society > 2008 > 130 > 34 > 11290 - 11291

article

The use of a detectable, mass-spectrometry-cleavable linker for quality control on an addressable microelectrode array

Ceng Chen, Peng Lu, Amy Walker, Karl Maurer, more

Electrochemistry Communications > 2008 > 10 > 7 > 973-976

The synthesis, site-selective placement, and TOF-SIMS cleavage properties of a new, fluorescent linker for attaching molecules to a microelectrode array are reported. The linker was developed to provide a handle for quality control assessment of the microelectrode arrays being used to probe the binding of molecular libraries with biological receptors.

article

Building Addressable Libraries: Site-Selective Formation of an N -Acyliminium Ion Intermediate

David Kesselring, Karl Maurer, Kevin D. Moeller

Organic Letters > 2008 > 10 > 12 > 2501 - 2504

article

Prometheus — göttlicher Mittler oder Rebell?

Karl Maurer

Neohelicon > 2007 > 34 > 1 > 11-26

Man hat in Dantes Hölle unter den Empörern gegen den höchsten Gott den Titanen Prometheus vermißt, aber die Vorstellungen des mittelalterlichen Dichters sind, wie schon die der christlichen Autoren der Spätantike, von dem Schöpfungsbericht Ovids (Met. 1, V. 76–86) geprägt, nach dem „der Iapetide“ den Menschen aus himmlischen und irdischen Elementen gebildet und ihm als einzigen unter den Geschöpfen...

article

Building Addressable Libraries: The Use of a Mass Spectrometry Cleavable Linker for Monitoring Reactions on a Microelectrode Array

Ceng Chen, Gabriella Nagy, Amy V. Walker, Karl Maurer, more

Journal of the American Chemical Society > 2006 > 128 > 50 > 16020 - 16021

article

Building Addressable Libraries: Site Selective Coumarin Synthesis and the “Real-Time” Signaling of Antibody−Coumarin Binding

Eden Tesfu, Kris Roth, Karl Maurer, Kevin D. Moeller

Organic Letters > 2006 > 8 > 4 > 709 - 712

article

Building Addressable Libraries: Spatially Isolated, Chip-Based Reductive Amination Reactions

Eden Tesfu, Karl Maurer, Kevin D. Moeller

Journal of the American Chemical Society > 2006 > 128 > 1 > 70 - 71

article

The Removal of the t -BOC Group by Electrochemically Generated Acid and Use of an Addressable Electrode Array for Peptide Synthesis

Karl Maurer, Andy McShea, Michael Strathmann, Kilian Dill

Journal of Combinatorial Chemistry > 2005 > 7 > 5 > 637 - 640

article

Building Addressable Libraries: The Use of Electrochemistry for Spatially Isolating a Heck Reaction on a Chip

Jun Tian, Karl Maurer, Eden Tesfu, Kevin D. Moeller

Journal of the American Chemical Society > 2005 > 127 > 5 > 1392 - 1393

article

Building Addressable Libraries: The Use of Electrochemistry for Generating Reactive Pd(II) Reagents at Preselected Sites on a Chip

Eden Tesfu, Karl Maurer, Steven R. Ragsdale, Kevin D. Moeller

Journal of the American Chemical Society > 2004 > 126 > 20 > 6212 - 6213

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Tetrahedron Letters (1)
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INFONA - science communication portal

Search results for: Karl Maurer

New Approaches to the Synthesis of Addressable Microarray Molecular Libraries

Microelectrode array biosensor for studying carbohydrate-mediated interactions

Site-Selective, Cleavable Linkers: Quality Control and the Characterization of Small Molecules on Microelectrode Arrays

Site-Selectively Functionalizing Microelectrode Arrays: The Use of Cu(I)-Catalysts

Building Addressable Libraries: The Use of “Safety-Catch” Linkers on Microelectrode Arrays

Building Addressable Libraries: Site-Selective Use of Pd(0) Catalysts on Microelectrode Arrays

A New Porous Reaction Layer for Developing Addressable Molecular Libraries

Building Addressable Libraries: Site-Selective Suzuki Reactions on Microelectrode Arrays

Building addressable libraries: a site-selective allyl alkylation reaction

Moving Known Libraries to an Addressable Array: A Site-Selective Hetero-Michael Reaction

Microelectrode Arrays and Ceric Ammonium Nitrate: A Simple Strategy for Developing New Site-Selective Synthetic Methods

The use of a detectable, mass-spectrometry-cleavable linker for quality control on an addressable microelectrode array

Building Addressable Libraries: Site-Selective Formation of an N -Acyliminium Ion Intermediate

Prometheus — göttlicher Mittler oder Rebell?

Building Addressable Libraries: The Use of a Mass Spectrometry Cleavable Linker for Monitoring Reactions on a Microelectrode Array

Building Addressable Libraries: Site Selective Coumarin Synthesis and the “Real-Time” Signaling of Antibody−Coumarin Binding

Building Addressable Libraries: Spatially Isolated, Chip-Based Reductive Amination Reactions

The Removal of the t -BOC Group by Electrochemically Generated Acid and Use of an Addressable Electrode Array for Peptide Synthesis

Building Addressable Libraries: The Use of Electrochemistry for Spatially Isolating a Heck Reaction on a Chip

Building Addressable Libraries: The Use of Electrochemistry for Generating Reactive Pd(II) Reagents at Preselected Sites on a Chip

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