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Metastasis rather than primary tumors determines prognosis and mortality in the majority of cancer patients. Detection of metastatic lesions is critical to determine prognosis and suitable treatments. We developed a method for identifying sentinel lymph node (SLN) metastasis, using combined ultrasound and photoacoustic (US/PA) imaging augmented with glycol-chitosan-coated gold nanoparticles (GC-AuNP)...
Microbubbles (MBs) are often used as ultrasound imaging contrast agents. Given their micrometer size, MBs are confined in vascular compartments because they cannot escape through endothelial barriers and, as such, MBs are primarily useful in microcirculation or vascular-targeting molecule imaging. To penetrate outside of vasculature, the size of the ultrasound contrast agent should be in the nanometer...
Metastasis rather than primary tumor determines prognosis and mortality in the majority of cancer patients. Detection of metastatic lesions is critical for diagnosis and staging, which helps establish the best course of treatment. We developed a method for identifying sentinel lymph node (SLN) metastasis, using combined ultrasound and photoacoustic (US/PA) imaging augmented with glycolchitosan-coated...
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