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Engineered polyethylene glycol‐maleimide matrices for regenerative medicine exhibit improved reaction efficiency and a wider range of Young's moduli by utilizing maleimide cross‐linking chemistry. This hydrogel chemistry is advantageous for cell delivery due to the mild reaction that occurs rapidly enough for in situ delivery, while easily lending itself to “plug‐and‐play” design variations such as...
The cover image shows a biofunctionalized hydrogel that is bonded directly onto myocardial tissue, delivering regenerative cells and therapeutics. On page 64, Andrés García and co‐workers describe how maleimide‐based cross‐linking improves polyethylene glycol hydrogel engineering, leading to rapid gelation, high cytocom‐patibility, and facile in situ delivery.
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