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Biominerals are most often considered in either their more traditional roles as critical structural components of organisms (e.g., teeth, the siliceous shell of diatoms) and important ion reservoirs for cellular function (Ca2+ and bone) or in their highly evolved functional roles (e.g., magnetotactic sensing, buoyancy/balance regulation). Increasingly, it is becoming apparent that biominerals also...
The Malaria Box, assembled by the Medicines for Malaria Venture, is a set of 400 structurally diverse, commercially available compounds with demonstrated activity against blood-stage Plasmodium falciparum. The compounds are a representative subset of the 20,000 in vitro antimalarials identified from the high-throughput screening efforts of St. Jude Children's Research Hospital (TN, USA), Novartis...
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