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Astrocytes associated with beta-amyloid (Aβ)-deposited senile plaques are a common neuropathological feature of Alzheimer's disease (AD). There is little doubt that the association of Aβ with the major component in the central nervous system cells significantly influences disease progression, however, the molecular mechanisms by which Aβ contributes to the astrocyte-mediated neuropathological changes...
Beta-amyloid (Aβ) deposition and senile plaque-associated astrocytes are common neuropathological features of Alzheimer's disease (AD). Although the molecular mechanisms by which Aβ contributes to the progression of neuropathologic changes have not been entirely established, there is little doubt that the association of Aβ with astrocytes, the predominant cell type in brain, significantly influences...
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