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To evaluate the feasibility of intratumoral delivery of adenoviral vector carrying a bidirectional two-step transcriptional amplification (TSTA) system to amplify transcriptional strength of cancer-specific Survivin promoter in a hepatocellular carcinoma model. MCA-RH7777 cells were implanted in rat liver, and tumor formation was confirmed with [ 18 F]fluorodeoxyglucose (18F-FDG) positron...
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