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A polydisperse aerosol inhalation system has been developed to measure particle deposition in the lungs of human subjects. Nebulizers are used to generate aerosols with mass median aerodynamic diameters from 0.3 to 3μm, and geometric standard deviations of 1.8-2.0. Inspired aerosol is drawn from a holding bag, passes through a sliding valve and a pneumotachograph, and enters a heated mouthpiece. Exhaled...
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