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Introduction
Prevalence of obesity and associated diseases, including type 2 diabetes mellitus, dyslipidaemia and non‐alcoholic fatty liver disease (NAFLD), are increasing. Underlying mechanisms, especially in humans, are unclear. Bariatric surgery provides the unique opportunity to obtain biopsies and portal vein blood‐samples.
Methods
The BARIA Study aims to assess how microbiota and their metabolites...
Mardinoglu A, Nielsen J (University of Technology, Gothenburg, Sweden). Systems medicine and metabolic modelling (Key Symposium). J Intern Med 2012; 271:142–154.
Several complex diseases are caused by the malfunction of human metabolism, and deciphering the underlying molecular mechanisms can elucidate their aetiology. Systems biology is an integrative approach combining experimental and computational...
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