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Massive amounts of sequencing data are being generated thanks to advances in sequencing technology and a dramatic drop in the sequencing cost. Much of the data are comprised of nucleotides and the corresponding quality scores that indicate their reliability. The latter are more difficult to compress and are themselves noisy. As a result, lossy compression of the quality scores has recently been proposed...
DNA sequencing technology has advanced to a point where storage is becoming the central bottleneck in the acquisition and mining of more data. Large amounts of data are vital for genomics research, and generic compression tools, while viable, cannot offer the same savings as approaches tuned to inherent biological properties. We propose an algorithm to compress a target genome given a known reference...
The mechanical property of the trachea affects the flow in the airway and may contribute to the biological function of the lung. Like many other biological tissues, the tracheal cartilage is likely to be a nonlinear material. To investigate the nonlinearity of tracheal cartilage, Fung-type strain energy density function was used. A mathematical model for analyzing the deformation of tracheal cartilage...
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