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We present the design of an automatic electrode monitoring system for activated iridium oxide (AIROF) microelectrodes. It's a valuable piece of instrument in use in our laboratory to monitor the "health" of chronic implanted microelectrodes before neural stimulation or recording experiments. It is capable of automatically measuring electrode voltage and current of a large number of electrodes...
Following the early work of Brindley in the late 1960's, the NIH began intramural and extramural funding for stimulation of the primary visual cortex using fine-wire electrodes that are inserted into area V1 for the purpose of restoring vision in individuals with blindness. More recently researchers with experience in this project became part of our multi-institutional team with the intention to identify...
Cyclic voltammetry (CV) at slow scan rate is usually performed to characterize the electrochemical behavior of microelectrodes. Early in vitro study on over 200 activated iridium oxide film (AIROF) microelectrodes showed variability of their electrochemical behavior. In this paper, we reported CV measurements under 3 different scan rates for 96 AIROF microelectrodes. We traced their behavior during...
We present the design and testing of a 96-channel stimulation system to drive activated iridium oxide (AIROF) microelectrodes within safe charge-injection limits. Our system improves upon the traditional capacitively coupled, symmetric charge-balanced biphasic stimulation waveform so as to maximize charge-injection capacity without endangering the microelectrodes. It can deliver computer-controlled...
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