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1. The effect of GABA receptor antagonists on baclofen-induced antinociception was examined in rats using the formalin test. Intraperitoneal (IP) administration of different doses of baclofen (2.5-10 mg kg -1 ) to rats induced antinociception in both phases of the test.2. The response was dose-dependent and the maximum response was observed with 10 mg kg -1 of the drug. ...
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