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To study the phylogeny and antigenic properties of HPV5 variants, we sequenced a 419 base pair-fragment located in the L1 capsid gene of 35 isolates from 33 patients suffering from epidermodysplasia verruciformis (EV). A high genetic heterogeneity (12.9% variable nucleotide positions) was found, resulting in the recognition of 3 HPV5 subgroups on the basis of amino acid sequence alignment. We constructed...
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