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Hypothalamic neurones that release the hormones vasopressin and oxytocin from the posterior pituitary are controlled, in part, by synaptic inputs mediated by the neurotransmitter GABA.GABA synapses on the vasopressin neurones, but not the oxytocin neurones, have been shown to elicit excitation.We show that brief (1 s) electrical stimulation of hypothalamus slices causes release of GABA lasting several...
Spike‐independent miniature postsynaptic currents are generally stochastic and are therefore not thought to mediate information relay in neuronal circuits. However, we recorded endogenous bursts of IPSCs in hypothalamic magnocellular neurones in the presence of TTX, which implicated a coordinated mechanism of spike‐independent GABA release. IPSC bursts were identical in the absence of TTX, although...
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