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Perfluoropentane (PFP) gas‐filled biodegradable iron‐doped silica nanoshells have been demonstrated as long‐lived ultrasound contrast agents. Nanoshells are synthesized by a sol–gel process with tetramethyl orthosilicate (TMOS) and iron ethoxide. Substituting a fraction of the TMOS with R‐substituted‐trialkoxysilanes produces ultrathin nanoshells with varying shell thicknesses and morphologies composed...
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