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Purpose
Myopia progression is thought to involve biomechanical weakening of the sclera, which leads to irreversible deformations and axial elongation of the eye. Scleral crosslinking has been proposed as a potential treatment option for myopia control by strengthening the mechanically weakened sclera. The biomechanical mechanism by which the sclera weakens during myopia and strengthens after crosslinking...
Adult bone diseases, especially osteoporosis, increase risk of fracture associated with substantial morbidity, mortality, and financial costs. Osteoporosis is clinically defined by low bone mineral density (BMD). However, increasing evidence suggests that trabecular bone (TB) micro-architectural quality is an important determinant of bone strength and fracture risk. Recently, a volumetric topological...
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