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Cells submitted to an electric field gradient experience dielectrophoresis. Such a force is useful for pairing cells prior to electrofusion. The latter event is induced by the application of electric field pulses leading to membrane fusion while cells are in physical contact. Nevertheless, the efficiency of dielectrophoretic pairing and electrofusion of cells are highly dependent on medium properties...
Direct continuous (DC), pulsed (PEF) or alternative (AC) electric fields are well-known to induce specific effects on living cells or on molecules (including DNA and proteins) and are commonly used in molecular or cellular biology, and more recently for clinical treatment. Pharmacological industries and medical research are interesting in the development of new tools permitting to understand biophysical...
MEMS, electromagnetic field is a way to manipulate droplets, beads or cells without direct contact. In particular, dielectrophoresis is often used in bioMEMS applications, for cell handling operations such as moving, sorting, trapping or deforming cells. In this paper, a 3D focusing geometry for the electrical field is proposed, that permit the trapping of single cell, or cells pair, thanks to positive...
This paper focuses on the application of dielectrophoresis to on-chip cell sorting. Differential dielectric affinity separation is a "binary" technique, dividing a cell mixture into two distinct sub-populations. The principle and efficiency of this method are illustrated by potential energy plots of cells exposed to negative and positive dielectrophoresis. This paper aims at comparing several...
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