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.Objectives and design:The objective of this study was to explore whether increased levels of inflammatory cytokines are associated with the risk of clinically silent coronary artery disease.Subjects:Three-hundred-fifty-six black adults aged 25–54 residing in inner city of Baltimore, Maryland, United States were included in this study.Methods:Sociodemographics were assessed as were lipid profiles,...
Objective and Design: To document in vivo immunolocalization and activation of nuclear factor-B (NF-B) and inducible nitric oxide synthase (iNOS) expression in prediabetic stages of diabetes mellitus. Material or Subjects: Genetic, diabetic-prone or diabetic-resistant BB rats (total = 189). Treatment: Various doses of an oral dithiocarbamate derivative, NOX-700, or cyclosporine (2.5 mg/kg) starting...
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