Search results for: Zdeněk Kadaňka

Items from 1 to 6 out of 6 results

article

Diffusion magnetic resonance imaging reveals tract‐specific microstructural correlates of electrophysiological impairments in non‐myelopathic and myelopathic spinal cord compression

Jan Valošek, René Labounek, Tomáš Horák, Magda Horáková, more

European Journal of Neurology > 28 > 11 > 3784 - 3797

Background and purpose Non‐myelopathic degenerative cervical spinal cord compression (NMDC) frequently occurs throughout aging and may progress to potentially irreversible degenerative cervical myelopathy (DCM). Whereas standard clinical magnetic resonance imaging (MRI) and electrophysiological measures assess compression severity and neurological dysfunction, respectively, underlying microstructural...

article

Spinal Cord MR Diffusion Properties in Patients with Degenerative Cervical Cord Compression

Miloš Keřkovský, Josef Bednařík, Barbora Jurová, Ladislav Dušek, more

Journal of Neuroimaging > 27 > 1 > 149 - 157

BACKGROUND AND PURPOSE Diffusion tensor imaging (DTI) has previously been used as a biomarker of myelopathy in patients with degenerative cervical cord compression (DCCC). However, many factors may affect the diffusion properties of the spinal cord. This prospective study seeks to identify sources of variability in spinal cord DTI parameters in both DCCC patients and healthy subjects. METHODS The...

article

Cervical spondylotic myelopathy: conservative versus surgical treatment after 10 years

Zdeněk Kadaňka, Josef Bednařík, Oldřich Novotný, Igor Urbánek, more

European Spine Journal > 2011 > 20 > 9 > 1533-1538

It is not known whether the results of decompressive surgery to treat the mild and moderate forms of spondylotic cervical myelopathy (CSM) are any better than those of a conservative approach. A 10-year prospective randomised study was performed. The objective of the study was to compare conservative and operative treatments of mild and moderate, non-progressive, or slowly progressive, forms of CSM...

article

Matrix metalloproteinase-9 and matrix metalloproteinase-2 gene polymorphisms in multiple sclerosis

Yvonne Benešová, Anna Vašků, Pavel Štourač, Magdalena Hladíková, more

Journal of Neuroimmunology > 2008 > 205 > 1-2 > 105-109

We investigated the association of matrix metalloproteinase-9 (−1562C/T, +279R/Q) and matrix metalloproteinase-2 (−1575G/A, −1306C/T) gene polymorphisms with multiple sclerosis (MS) susceptibility, gender differences and disability in 244 patients and 132 healthy subjects. A significant decrease of the −1562T allele carriers in MS patients compared to controls (Pa=0.01, Pacorr=0.05) in −1562C/T MMP-9...

article

Presymptomatic spondylotic cervical myelopathy: an updated predictive model

Josef Bednarik, Zdenek Kadanka, Ladislav Dusek, Milos Kerkovsky, more

European Spine Journal > 2008 > 17 > 3 > 421-431

Spondylotic cervical cord compression detected by imaging methods is a prerequisite for the clinical diagnosis of spondylotic cervical myelopathy (SCM). Little is known about the spontaneous course and prognosis of clinically “silent” presymptomatic spondylotic cervical cord compression (P-SCCC). The aim of the present study was to update a previously published model predictive for the development...

article

A mutation in the X-linked Emery-Dreifuss muscular dystrophy gene in a patient affected with conduction cardiomyopathy

Stanislav Vohanka, Michal Vytopil, Josef Bednarik, Zdenek Lukas, more

Neuromuscular Disorders > 2001 > 11 > 4 > 411-413

A screening for mutation in the X-linked Emery-Dreifuss muscular dystrophy (X-EMD) gene was performed among patients affected with severe heart rhythm defects and/or dilated cardiomyopathy. Patients were selected from the database of the Department of Cardiology of the University Hospital Brno. One patient presented a mutation in the X-EMD gene and no emerin in his skeletal muscle. The patient had...

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Keywords

DIFFUSION TENSOR IMAGING (2)
CERVICAL SPONDYLOSIS (1)
CERVICAL SPONDYLOTIC MYELOPATHY (1)
CONDUCTION CARDIOMYOPATHY (1)
CONSERVATIVE TREATMENT (1)
DEGENERATIVE CERVICAL CORD COMPRESSION (1)
DEGENERATIVE CERVICAL MYELOPATHY (1)
DIFFUSION MAGNETIC RESONANCE IMAGING (1)
ELECTROMYOGRAPHY (1)
EMERY-DREIFUSS MUSCULAR DYSTROPHY (1)
EVOKED POTENTIALS (1)
GENE (1)
MAGNETIC RESONANCE IMAGING (1)
MATRIX METALLOPROTEINASES (1)
MULTIPLE SCLEROSIS (1)
MUTATIONS (1)
POLYMORPHISM (1)
SPINAL CORD COMPRESSION (1)
SPONDYLOTIC CERVICAL CORD COMPRESSION (1)
SPONDYLOTIC CERVICAL MYELOPATHY (1)
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Search results for: Zdeněk Kadaňka

Diffusion magnetic resonance imaging reveals tract‐specific microstructural correlates of electrophysiological impairments in non‐myelopathic and myelopathic spinal cord compression

Spinal Cord MR Diffusion Properties in Patients with Degenerative Cervical Cord Compression

Cervical spondylotic myelopathy: conservative versus surgical treatment after 10 years

Matrix metalloproteinase-9 and matrix metalloproteinase-2 gene polymorphisms in multiple sclerosis

Presymptomatic spondylotic cervical myelopathy: an updated predictive model

A mutation in the X-linked Emery-Dreifuss muscular dystrophy gene in a patient affected with conduction cardiomyopathy

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