Search results for: Petro Starokadomskyy

Items from 1 to 4 out of 4 results

article

Microbial Sensing by Intestinal Myeloid Cells Controls Carcinogenesis and Epithelial Differentiation

Naoteru Miyata, Lindsey L. Morris, Qing Chen, Curtis Thorne, more

Cell Reports > 2018 > 24 > 9 > 2342-2355

Physiologic microbe-host interactions in the intestine require the maintenance of the microbiota in a luminal compartment through a complex interplay between epithelial and immune cells. However, the roles of mucosal myeloid cells in this process remain incompletely understood. In this study, we identified that decreased myeloid cell phagocytic activity promotes colon tumorigenesis. We show that this...

article

Are viruses alive? The replicator paradigm sheds decisive light on an old but misguided question

Eugene V. Koonin, Petro Starokadomskyy

Studies in History and Philosophy of Science Part C: Studies in History... > 2016 > 59 > C > 125-134

The question whether or not “viruses are alive” has caused considerable debate over many years. Yet, the question is effectively without substance because the answer depends entirely on the definition of life or the state of “being alive” that is bound to be arbitrary. In contrast, the status of viruses among biological entities is readily defined within the replicator paradigm. All biological replicators...

article

331 Intestinal Dysbiosis and Susceptibility to Colonic Neoplasia Are Controlled by Myeloid Cell Intrinsic Factors

Naoteru Miyata, Wenhan Zhu, Haiying Li, Kayci Huff-Hardy, more

Gastroenterology > 2016 > 150 > 4(S1) > S78

article

Copper Metabolism Domain-Containing 1 Represses Genes That Promote Inflammation and Protects Mice From Colitis and Colitis-Associated Cancer

Haiying Li, Lillienne Chan, Paulina Bartuzi, Shelby D. Melton, more

Gastroenterology > 2014 > 147 > 1 > 184-195.e3

Activation of the transcription factor nuclear factor-κB (NF-κB) has been associated with the development of inflammatory bowel disease (IBD). Copper metabolism MURR1 domain containing 1 (COMMD1), a regulator of various transport pathways, has been shown to limit NF-κB activation. We investigated the roles of COMMD1 in the pathogenesis of colitis in mice and IBD in human beings.We created mice with...

INFONA - science communication portal

Search results for: Petro Starokadomskyy

Microbial Sensing by Intestinal Myeloid Cells Controls Carcinogenesis and Epithelial Differentiation

Are viruses alive? The replicator paradigm sheds decisive light on an old but misguided question

331 Intestinal Dysbiosis and Susceptibility to Colonic Neoplasia Are Controlled by Myeloid Cell Intrinsic Factors

Copper Metabolism Domain-Containing 1 Represses Genes That Promote Inflammation and Protects Mice From Colitis and Colitis-Associated Cancer

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INFONA - science communication portal

Search results for: Petro Starokadomskyy

Microbial Sensing by Intestinal Myeloid Cells Controls Carcinogenesis and Epithelial Differentiation

Are viruses alive? The replicator paradigm sheds decisive light on an old but misguided question

331 Intestinal Dysbiosis and Susceptibility to Colonic Neoplasia Are Controlled by Myeloid Cell Intrinsic Factors

Copper Metabolism Domain-Containing 1 Represses Genes That Promote Inflammation and Protects Mice From Colitis and Colitis-Associated Cancer

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