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BACKGROUNDThe Magnetic Resonance Imaging (MRI)‐guided focal laser therapy has shown early promise in Phase 1 trial treating low/intermediate‐risk localized prostate cancer (PCa), but the lack of tumor selectivity and low efficiency of heat generation remain as drawbacks of agent‐free laser therapy. Intrinsic multifunctional porphyrin‐nanoparticles (porphysomes) have been exploited to treat localized...
The discovery and synthesis of novel multifunctional organic building blocks for nanoparticles is challenging. Texaphyrin macrocycles are capable and multifunctional chelators. However, they remain elusive as building blocks for nanoparticles because of the difficulty associated with synthesis of texaphyrin constructs capable of self‐assembly. A novel manganese (Mn)‐texaphyrin‐phospholipid building...
To analyze the pathogenesis of persistent and refractory haematospermia and to evaluate the aetiological diagnostic value of magnetic resonance imaging (MRI) for this type of haematospermia. Clinical data from 102 patients with persistent and refractory haematospermia was retrospectively analysed. Data collected included history, symptoms, as well as ultrasound and MRI of the morphological features...
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