Cytogenetically normal acute myeloid leukemia (CN‐AML), which accounted for nearly half of total AML patients, is a highly heterogeneous subset of AML. The specific genetic profile and the ethnic features of CN‐AML are worth to be studied.
Using deep sequencing technology, we detected the mutation pattern of 39 genes in 152 Chinese CN‐AML patients and analyzed their clinical...
IntroductionGlucose‐6‐phosphate dehydrogenase (G6PD) deficiency is highly prevalent in southern China. The aim of this study is to assess the extent of this disease in Chinese neonates and determine its molecular characteristics using a novel molecular screening method.
MethodsA total of 2500 neonates were routinely screened for G6PD deficiency using a modified fluorescent spot test (FST). PCR‐high‐resolution...
Financed by the National Centre for Research and Development under grant No. SP/I/1/77065/10 by the strategic scientific research and experimental development program:
SYNAT - “Interdisciplinary System for Interactive Scientific and Scientific-Technical Information”.