Search results for: György Nagy

Items from 1 to 20 out of 34 results

article

Primary antiphospholipid syndrome and antiphospholipid syndrome associated to systemic lupus: Are they different entities?

Cristina Belizna, Ljudmila Stojanovich, Jan Willem Cohen-Tervaert, Céline Fassot, more

Autoimmunity Reviews > 2018 > 17 > 8 > 739-745

Primary antiphospholipid syndrome (PAPS) and antiphospholipid syndrome associated to lupus (SAPS) have several overlapping characteristics. As systemic manifestations are also reported in patients with PAPS, and as a subgroup of PAPS patients could evaluate to a SAPS, the differentiation between the two types of APS could be performed based on the clinical experience of the medical teams and is related...

article

Biomarkers for rheumatoid arthritis: From molecular processes to diagnostic applications-current concepts and future perspectives

Britt Nakken, Gábor Papp, Vidar Bosnes, Margit Zeher, more

Immunology Letters > 2017 > 189 > C > 13-18

Early diagnosis and immediately started appropriate treatment are mandatory for the prevention of radiographic progression, functional disability and unfavourable disease outcome in rheumatoid arthritis (RA). The current classification criteria for RA include two different types of biomarkers representing inflammatory processes, such as C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR)...

article

Extracellular vesicles regulate the human osteoclastogenesis: divergent roles in discrete inflammatory arthropathies

Nikolett Marton, Orsolya Tünde Kovács, Eszter Baricza, Ágnes Kittel, more

Cellular and Molecular Life Sciences > 2017 > 74 > 19 > 3599-3611

Objective Extracellular vesicles (EVs) are subcellular signalosomes. Although characteristic EV production is associated with numerous physiological and pathological conditions, the effect of blood-derived EVs on bone homeostasis is unknown. Herein we evaluated the role of circulating EVs on human osteoclastogenesis. Methods Blood samples from healthy volunteers, rheumatoid arthritis (RA) and psoriatic...

article

Chronic pancreatitis: Refinement of multicentre prospective data collection and analysis by the Hungarian Pancreatic Study Group

Ákos Szücs, Szilárd Gódi, Adrienn Halász, Balázs Kui, more

Pancreatology > 2016 > 16 > 3(S1) > S69

article

The emerging role of aryl hydrocarbon receptor in the activation and differentiation of Th17 cells

Eszter Baricza, Viola Tamási, Nikolett Marton, Edit I. Buzás, more

Cellular and Molecular Life Sciences > 2016 > 73 > 1 > 95-117

The aryl hydrocarbon receptor (AHR) is a cytoplasmic transcription factor, which plays an essential role in the xenobiotic metabolism in a wide variety of cells. The AHR gene is evolutionarily conserved and it has a central role not only in the differentiation and maturation of many tissues, but also in the toxicological metabolism of the cell by the activation of metabolizing enzymes. Several lines...

article

In vitro eradication of citrullinated protein specific B-lymphocytes of rheumatoid arthritis patients by targeted bifunctional nanoparticles

Judit Pozsgay, Fruzsina Babos, Katalin Uray, Anna Magyar, more

Arthritis Research & Therapy > 2016 > 18 > 1 > 1-12

Background Autoreactive B cells are crucial players in the pathogenesis of rheumatoid arthritis (RA). Autoantibodies specific for citrullinated proteins (ACPA), present in the serum of approximately 60–70 % of patients, have a pathogenic role in the disease. B cell depleting therapies may result in a transient immunosuppression, increasing the risk of infections. Our aim was to develop a new therapeutic...

article

Chronic pancreatitis. Multicentre prospective data collection and analysis by the Hungarian Pancreatic Study Group

Akos Szucs, Szilard Godi, Adrienn Halasz, Balazs Kui, more

Pancreatology > 2015 > 15 > 3 Supplement > S76

article

Sustained biologic-free and drug-free remission in rheumatoid arthritis, where are we now?

György Nagy, Ronald F van Vollenhoven

Arthritis Research & Therapy > 2015 > 17 > 1 > 1-7

The advent of new medications and new treatment strategies for rheumatoid arthritis has made it possible to achieve remission in more patients than before. Furthermore, recent clinical trials and register studies suggest that some patients who initially required aggressive therapy may achieve biologic-free remission or even the ultimate goal of therapy, drug-free remission, resembling recovery. Here,...

article

Recognition of new citrulline‐containing peptide epitopes by autoantibodies produced in vivo and in vitro by B cells of rheumatoid arthritis patients

Eszter Szarka, Fruzsina Babos, Anna Magyar, Krisztina Huber, more

Immunology > 141 > 2 > 181 - 191

Anti‐citrullinated peptide/protein antibodies (ACPAs) are highly sensitive and specific markers of rheumatoid arthritis (RA). Identification of peptide epitopes that may detect different subgroups of RA patients might have diagnostic and prognostic significance. We have investigated citrulline‐ and arginine‐containing peptide pairs derived from filaggrin, collagen or vimentin, and compared this citrulline‐peptide...

article

Efficacy and safety of infliximab-biosimilar compared to other biological drugs in rheumatoid arthritis: a mixed treatment comparison

Petra Baji, Márta Péntek, László Czirják, Zoltán Szekanecz, more

The European Journal of Health Economics > 2014 > 15 > 1 > 53-64

Objective The aim of this meta-analysis was to compare the efficacy and safety of infliximab-biosimilar and other available biologicals for the treatment of rheumatoid arthritis (RA), namely abatacept, adalimumab, certolizumab pegol, etanercept, golimumab, infliximab, rituximab and tocilizumab. Methods A systematic literature review of MEDLINE database until August 2013 was carried out to identify...

article

Treatment of Refractory Hairy Cell Leukemia with a BRAF-inhibitor: Lessons to be Learnt

Eszter Sári, Zsolt György Nagy, Kornélia Baghy, Hajnalka Rajnai, more

Pathology & Oncology Research > 2014 > 20 > 4 > 973-980

Hairy cell leukemia is a rare chronic lymphoproliferative disorder with indolent but progressive clinical course. Patients require treatment when they have significant cytopenia or recurrent infections. The gold standard treatment are purine nucleoside analogues (cladribine and pentostatine), with these agents the rate of complete remission can approach even 95 %. The differential diagnosis between...

chapter

Enhancing Wireless Sensor Networks with Acoustic Sensing Technology: Use Cases, Applications & Experiments

Danilo Hollosi, Gyorgy Nagy, Rene Rodigast, Stefan Goetze, more

2013 IEEE International Conference on Green Computing and Communications and IEEE Internet of Things and IEEE Cyber, Physical and Social Computing > 335 - 342

2013 IEEE International Conference on Green Computing and Communications (GreenCom) and IEEE Internet of Things(iThings) and IEEE Cyber, Physical and Social Computing(CPSCom)

This paper presents research carried out within the EU FP7 EAR-IT project, which is working on the challenges of bringing acoustic sensing intelligence to large-scale indoor and outdoor wireless sensor networks, i.e. into two existing test beds out of the EU FP7 FIRE projects SmartSantander and Hobnet. Besides the benefits by integrating machine-learning based acoustic sensing technology, the general...

article

Announcements

György Nagy

European Journal of Clinical Investigation > 43 > 8 > 885 - 885

article

The role of citrullination of an immunodominant proteoglycan (PG) aggrecan T cell epitope in BALB/c mice with PG-induced arthritis

Petra Misják, Szilvia Bősze, Kata Horváti, Mária Pásztói, more

Immunology Letters > 2013 > 152 > 1 > 25-31

The P70-84 peptide (also called 5/4E8 epitope) of the human cartilage proteoglycan (PG) aggrecan is the dominant/arthritogenic epitope in both humans and arthritis-prone BALB/c mice (PG-induced arthritis, PGIA). An elevated T cell reactivity was demonstrated to a citrullinated version of the P70-84 epitope in most of the patients with rheumatoid arthritis (RA). The goal of this study was to understand...

article

La citrullination en situations normale et pathologique

Zsuzsanna Baka, Bence György, Pál Géher, Edit I. Buzás, more

Revue du rhumatisme > 2013 > 80 > 1 > 18-24

La citrullination, modification enzymatique post-traductionnelle, est un sujet d’actualité très développé récemment en raison de son implication dans divers processus physiologiques et pathologiques. Les anticorps antiprotéines citrullinées constituent des facteurs diagnostiques et pronostiques de la polyarthrite rhumatoïde, et sont spécifiques de cette maladie. La citrullination a un rôle important...

article

The recently identified hexosaminidase D enzyme substantially contributes to the elevated hexosaminidase activity in rheumatoid arthritis

Mária Pásztói, Barbara Sódar, Petra Misják, Krisztina Pálóczi, more

Immunology Letters > 2013 > 149 > 1-2 > 71-76

Since the 1970s, numerous reports have described elevated hexosaminidase activities in rheumatoid arthritis. However, due to the overlapping substrate specificities of different hexosaminidases, identification of the exact enzyme(s) responsible for the elevated activity remains incomplete.In this work we tested if the recently described enzyme, hexosaminidase D was expressed in human arthritic joints,...

article

Non-synonymous single nucleotide polymorphisms in genes for immunoregulatory galectins: Association of galectin-8 (F19Y) occurrence with autoimmune diseases in a Caucasian population

Zsuzsanna Pál, Péter Antal, Sanjeev Kumar Srivastava, Gábor Hullám, more

BBA - General Subjects > 2012 > 1820 > 10 > 1512-1518

Galectins are potent immune regulators, with galectin-8 acting as a pro-apoptotic effector on synovial fluid cells and thymocytes and stimulator on T-cells. To set a proof-of-principle example for risk assessment in autoimmunity, and for a mutation affecting physiological galectin sensor functions, a polymorphism in the coding region of the galectin-8 gene (rs2737713; F19Y) was studied for its association...

article

Citrullination under physiological and pathological conditions

Zsuzsanna Baka, Bence György, Pál Géher, Edit I. Buzás, more

Joint Bone Spine > 2012 > 79 > 5 > 431-436

Citrullination, one of the enzymatic posttranslational modifications has become a hot topic of recent research as it is involved in various physiological and pathological processes. Antibodies against citrullinated proteins called anti-citrullinated protein antibodies, are the hallmark (diagnostic and prognostic factors) of rheumatoid arthritis, and are specific for the disease. Citrullination has...

article

The effect of balneotherapy on antioxidant, inflammatory, and metabolic indices in patients with cardiovascular risk factors (hypertension and obesity)—A randomised, controlled, follow-up study

Mihály Oláh, Ágnes Koncz, Judit Fehér, Judit Kálmánczhey, more

Contemporary Clinical Trials > 2011 > 32 > 6 > 793-801

The primary objective of our study was to explore the changes of antioxidant, inflammatory, and metabolic parameters in obese and hypertension people patients during balneotherapy and to evaluate the safety of balneotherapy in these participants.Following randomisation, 22 obese and 20 hypertensive patients underwent balneotherapy with thermal water of 38°C temperature, in 15 sessions of 30 minutes...

article

Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles

Bence György, Tamás G. Szabó, Mária Pásztói, Zsuzsanna Pál, more

Cellular and Molecular Life Sciences > 2011 > 68 > 16 > 2667-2688

Release of membrane vesicles, a process conserved in both prokaryotes and eukaryotes, represents an evolutionary link, and suggests essential functions of a dynamic extracellular vesicular compartment (including exosomes, microparticles or microvesicles and apoptotic bodies). Compelling evidence supports the significance of this compartment in a broad range of physiological and pathological processes...

Publication date

Set your own date range

INFONA - science communication portal

Search results for: György Nagy

Primary antiphospholipid syndrome and antiphospholipid syndrome associated to systemic lupus: Are they different entities?

Biomarkers for rheumatoid arthritis: From molecular processes to diagnostic applications-current concepts and future perspectives

Extracellular vesicles regulate the human osteoclastogenesis: divergent roles in discrete inflammatory arthropathies

Chronic pancreatitis: Refinement of multicentre prospective data collection and analysis by the Hungarian Pancreatic Study Group

The emerging role of aryl hydrocarbon receptor in the activation and differentiation of Th17 cells

In vitro eradication of citrullinated protein specific B-lymphocytes of rheumatoid arthritis patients by targeted bifunctional nanoparticles

Chronic pancreatitis. Multicentre prospective data collection and analysis by the Hungarian Pancreatic Study Group

Sustained biologic-free and drug-free remission in rheumatoid arthritis, where are we now?

Recognition of new citrulline‐containing peptide epitopes by autoantibodies produced in vivo and in vitro by B cells of rheumatoid arthritis patients

Efficacy and safety of infliximab-biosimilar compared to other biological drugs in rheumatoid arthritis: a mixed treatment comparison

Treatment of Refractory Hairy Cell Leukemia with a BRAF-inhibitor: Lessons to be Learnt

Enhancing Wireless Sensor Networks with Acoustic Sensing Technology: Use Cases, Applications & Experiments

Announcements

The role of citrullination of an immunodominant proteoglycan (PG) aggrecan T cell epitope in BALB/c mice with PG-induced arthritis

La citrullination en situations normale et pathologique

The recently identified hexosaminidase D enzyme substantially contributes to the elevated hexosaminidase activity in rheumatoid arthritis

Non-synonymous single nucleotide polymorphisms in genes for immunoregulatory galectins: Association of galectin-8 (F19Y) occurrence with autoimmune diseases in a Caucasian population

Citrullination under physiological and pathological conditions

The effect of balneotherapy on antioxidant, inflammatory, and metabolic indices in patients with cardiovascular risk factors (hypertension and obesity)—A randomised, controlled, follow-up study

Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles

Filter options

Publication date

Publication type

Publication language

Keywords

Data set

Journal

INFONA - science communication portal

Search results for: György Nagy

Add recipient

Sending message cancelled

Are you sure you want to cancel sending this message?

Send message

Filter options

Publication date

Date range setting

Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.

Publication type

Publication language

Keywords

Data set

Journal

Reporting an error / abuse

Sending the report failed

Accessibility options