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Objectives
The aim of the study was to investigate the efficacy and safety of first‐line antiretroviral therapy (ART) with integrase inhibitor (INI) or protease inhibitor (PI)‐based regimens in patients with low CD4 cell counts and/or an AIDS‐defining disease.
Methods
We conducted a retrospective, multicentre analysis to investigate discontinuation proportions and virological response in patients...
ObjectivesThe aim of the study was to assess pregnancy complications in HIV‐positive women and changes in the rates of such complications over 11 years in the Frankfurt HIV Cohort.
MethodsThere were 330 pregnancies in HIV‐positive women between 1 January 2002 and 31 December 2012. The rate of pregnancy‐related complications, such as gestational diabetes mellitus (GDM), pre‐eclampsia and preterm delivery,...
ObjectivesRenal disease is a common and serious complication in HIV‐infected patients.
MethodsA retrospective cohort analysis for the period 1989–2010 was carried out to determine the prevalence, incidence and risk factors for end‐stage renal disease (ESRD). ESRD was defined as initiation of renal replacement therapy. Three time periods were defined: 1989–1996 [pre‐highly active antiretroviral therapy...
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