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Streptococcus equi is a horse pathogen belonging to Lancefield group C. Infection by S. equi ssp. equi causes strangles, a serious and highly contagious disease of the upper respiratory tract. S. equi ssp. equi secretes a fibronectin (Fn)‐binding protein, FNE, that does not contain cell wall‐anchoring motifs. FNE binds to the gelatin‐binding domain (GBD) of Fn, composed of the motifs 6FI12FII789FI...
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