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Nowadays, cells are commonly used for predicting whether the drug compounds will be effective and safe in human. The response of cell groups was usually analyzed, instead of single cell. However, individual cells within the same population even shows various characteristics. Understanding this heterogeneity is critical to studying how effective therapies will be in the clinic. Therefore, highly efficient...
This paper presents a new method of microfluidic chip fabrication using 3D design and 3D printing techniques. The printed materials are flexible and inexpensive. The fabrication procedure is time-saving and less complex. The water leakage and hydrophilic test are performed to prove the advantages over traditional methods. The flow rates of the printed pump chip have been tested under varied applied...
Patterned microstructures of hydrogels have attracted significant attention due to an increasing need for developing scaffolds for tissue engineering, as carriers for drug delivery, and as extracellular matrices for biological studies. However, current tissue engineering approaches lack the flexibility required for developing complex two or three-dimensional (2D/3D) microstructures, which are used...
Atomic force microscopy (AFM) and dielectrophoresis (DEP) technologies have been used as excellent tools for nanomanipulation and nanoassembly. AFM-based manipulation exhibits excellent positioning and very high accuracy. The advantage of DEP is its ability to carry out parallel and massive manipulation of nanomaterials. In this study, we develop AFM tip-induced dielectrophoresis for three dimensional...
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