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External radiotherapy is extensively used in clinic to destruct tumors by locally applied ionizing‐radiation beams. However, the efficacy of radiotherapy is usually limited by tumor hypoxia‐associated radiation resistance. Moreover, as a local treatment technique, radiotherapy can hardly control tumor metastases, the major cause of cancer death. Herein, core–shell nanoparticles based poly(lactic‐co...
Despite the promises of applying nano‐photosensitizers (nano‐PSs) for photodynamic therapy (PDT) against cancer, severe tumor hypoxia and limited tumor penetration of nano‐PSs would lead to nonoptimized therapeutic outcomes of PDT. Therefore, herein a biocompatible nano‐PS is prepared by using tamoxifen (TAM), an anti‐estrogen compound, to induce self‐assembly of chlorin e6 (Ce6) modified human serum...
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