Search results for: Michelle Vo

Items from 1 to 6 out of 6 results

article

Postdischarge health resource use in pediatric survivors of prolonged mechanical ventilation for acute respiratory illness

Michelle Vo, Kristen Miller, Tellen D. Bennett, Peter M. Mourani, more

Pediatric Pulmonology > 57 > 7 > 1651 - 1659

We aimed to identify characteristics associated with postdischarge health resource use in children without medical complexity who survived an episode of prolonged mechanical ventilation for respiratory illness. We hypothesized that longer durations of mechanical ventilation, noncomplex chronic conditions, and severe acute respiratory distress syndrome (ARDS) would be associated with readmission or...

article

Effector T cell function rather than survival determines extent and duration of hepatitis in mice

Michelle Vo, Lauren E. Holz, Yik Chun Wong, Kieran English, more

Journal of Hepatology > 2016 > 64 > 6 > 1327-1338

Acute hepatitis is often mediated by cytotoxic T lymphocytes (CTLs); however, the intrinsic parameters that limit CTL-mediated liver injury are not well understood.To investigate whether acute liver damage is limited by molecules that decrease the lifespan or effector function of CTLs, we used a well-characterized transgenic (Tg) mouse model in which acute liver damage develops upon transfer of T...

article

Naïve CD8 T cell activation by liver bone marrow-derived cells leads to a “neglected” IL-2low Bimhigh phenotype, poor CTL function and cell death

Lauren E. Holz, Volker Benseler, Michelle Vo, Claire McGuffog, more

Journal of Hepatology > 2012 > 57 > 4 > 830-836

The occurrence of primary CD8 T cell activation within the liver, unique among the non-lymphoid organs, is now well accepted. However, the outcome of intrahepatic T cell activation remains controversial. We have previously reported that activation initiated by hepatocytes results in a tolerogenic phenotype characterized by low expression of CD25 and IL-2, poor cytotoxic T lymphocyte (CTL) function,...

article

Increased mortality in patients with conflicting diastolic parameters

Samira Bahrainy, Michelle Vo, Edward A. Gill

The International Journal of Cardiovascular Imaging > 2012 > 28 > 4 > 735-741

The aim of this study was to describe the clinical characteristics and mortality of patients with conflicting diastolic function during follow-up. Up to 30% of patients have conflicting diastolic function by echo Doppler and therefore cannot be classified into a distinct diastolic dysfunction category of stage 1, 2 or 3. Using our established echocardiography data base, we studied a cohort of 250...

article

Body Mass Index and Adult Weight Gain Among Reproductive Age Women With Migraine

Michelle Vo, Abinnet Ainalem, Chunfang Qiu, B. Lee Peterlin, more

Headache: The Journal of Head and Face Pain > 51 > 4 > 559 - 569

(Headache 2011;51:559‐569) Objective.— To evaluate the cross‐sectional relationship between migraine and pregravid obesity; and to assess the risk of adult weight gain among women with history of a pediatric diagnosis of migraine. Background.— Obesity, comorbid with pain disorders including migraine, shares common pathophysiological characteristics including systemic inflammation, and derangements...

article

Invading macrophages play a major role in the liver progenitor cell response to chronic liver injury

Cornelia S. Viebahn, Volker Benseler, Lauren E. Holz, Caryn L. Elsegood, more

Journal of Hepatology > 2010 > 53 > 3 > 500-507

Although a strong association between liver progenitor cells (LPCs) and inflammation exists in many chronic liver diseases, the exact role of the immune system in LPC-mediated hepatic regeneration remains unclear. A number of pro-inflammatory factors were identified in cytokine knockout mice in which the LPC response was attenuated but neither the mechanism nor the producing cells are known.To identify...

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Search results for: Michelle Vo

Postdischarge health resource use in pediatric survivors of prolonged mechanical ventilation for acute respiratory illness

Effector T cell function rather than survival determines extent and duration of hepatitis in mice

Naïve CD8 T cell activation by liver bone marrow-derived cells leads to a “neglected” IL-2low Bimhigh phenotype, poor CTL function and cell death

Increased mortality in patients with conflicting diastolic parameters

Body Mass Index and Adult Weight Gain Among Reproductive Age Women With Migraine

Invading macrophages play a major role in the liver progenitor cell response to chronic liver injury

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