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Choosing Wisely is a medical stewardship and quality‐improvement initiative led by the American Board of Internal Medicine Foundation in collaboration with leading medical societies in the United States. The American Society of Hematology (ASH) has been an active participant in the Choosing Wisely project. In 2019, ASH and the American Society of Pediatric Hematology/Oncology (ASPHO) formed a joint...
BackgroundThrombosis in patients with acute lymphocytic leukemia (ALL) can develop after treatment with L‐asparaginase (asp) and is often localized to the central nervous system (CNS). We hypothesize that changes in the cerebrospinal fluid (CSF) proteome will occur after asp therapy and will anticipate CNS clots.
MethodsFive newly diagnosed patients, ages 1–11 years, with ALL (n = 4) or lymphoblastic...
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