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Alpha 1D -adrenoceptors (α 1D -ARs) located in the spinal cord are involved in the control of lower urinary tract function. In order to clarify the effect of α 1D -ARs on storage function in the spinal cord, we examined the effect of oral administration and intrathecal injection of the α 1D/A -AR antagonist, naftopidil, on bladder activity, as well as the effect of...
To confirm the role of alpha1-adrenoceptor (α 1 -AR) in the spinal cord, we investigated the effect of intrathecal application of terazosin, a non-selective α 1 -AR blocker, on the micturition reflex, as well as the change of α 1 -AR subtypes mRNA in the lumbosacral spinal cord using spinal cord injury (SCI) rats.Adult female Sprague–Dawley rats were used 4weeks after Th9–10...
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