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To further clarify the mechanism involved in the enhancement effect of lipid disperse systems (LDS) on percutaneous absorption, the effect of particle size of LDSs on percutaneous absorption of betahistine (BH), the comparison of the enhancement effect of LDS with the lipid mixtures or the plain LDS, the effect of pretreatment of skin with gel formulation on penetration of LDS-BH and the fluidising...
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