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Electrical stimulation of the neurones in the hypothalamic arcuate nucleus results in a transient inhibition followed by a marked post-stimulus excitation of magnocellular neurones of the supraoptic nucleus. Microdialysis administration of the γ-aminobutyric acid agonist (GABA A ), muscimol, directly into the supraoptic nucleus inhibited both oxytocin and vasopressin neurones and these actions...
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