Search results for: Iwona Stawoska

Items from 1 to 8 out of 8 results

article

Spectral Characteristic and Preliminary Anticancer Activity in vitro of Selected Rhodanine‐3‐carboxylic Acids Derivatives

Iwona Stawoska, Waldemar Tejchman, Olga Mazuryk, Antonín Lyčka, more

Journal of Heterocyclic Chemistry > 54 > 5 > 2889 - 2897

Selected rhodanine‐3‐carboxylic acids derivatives were synthesized to determine the influence of the structure and the length of the linker between the carboxyl group and the nitrogen atom (N‐3) in the 2‐thioxo‐4‐thiazolidinone ring on their activity, monitored via interactions with human serum albumin. Based on fluorescence studies, we concluded that the length of the linker has a limited impact...

article

Photosynthesis and sucrose metabolism in leaves of Arabidopsis thaliana aos, ein4 and rcd1 mutants as affected by wounding

Edyta Lukaszuk, Magdalena Rys, Katarzyna Możdżeń, Iwona Stawoska, more

Acta Physiologiae Plantarum > 2017 > 39 > 1 > 1-12

We have investigated the influence of mechanical wounding of Arabidopsis rosette leaves on photochemical activity of photosystem II, gas exchange, sugar content and sucrose metabolism in wild-type plants and mutants impaired in hormonal balance. The aos (jasmonate deficiency), rcd1 (reduced sensitivity to ABA, ethylene, and methyl-jasmonate), and ein4 (ethylene insensitivity) mutants have been used...

article

Metabolic response of cornflower (Centaurea cyanus L.) exposed to tribenuron-methyl: one of the active substances of sulfonylurea herbicides

Diana Saja, Magdalena Rys, Iwona Stawoska, Andrzej Skoczowski

Acta Physiologiae Plantarum > 2016 > 38 > 7 > 1-13

Tribenuron-methyl is the active substance of the herbicide used for weed control in crops. The aim of this study was to investigate differences in the metabolic response of seeds, seedlings and leaves of Centaurea cyanus L., depending on the degree of resistance to tribenuron-methyl. Changes in the values of selected biochemical and physiological parameters (germination index, chemical composition,...

article

FT-Raman spectroscopy as a tool in evaluation the response of plants to drought stress

Magdalena Rys, Maciej Szaleniec, Andrzej Skoczowski, Iwona Stawoska, more

Open Chemistry > 2015 > 13 > 1

The aim of study was to evaluate the usefulness of FT-Raman spectroscopy in assessing stress-induced metabolic changes in plants. 20-d-old optimally watered plants of soybean were exposed to drought. Metabolic changes in optimally watered and drought-stressed plants were monitored using FT-Raman spectroscopy. In parallel, analyses were carried out of fatty acid composition and pigment content using...

article

Interaction of selected divalent metal ions with human ataxin-3 Q36

Iwona Stawoska, Aleksandra Wesełucha-Birczyńska, Maria Elena Regonesi, Matteo Riva, more

JBIC Journal of Biological Inorganic Chemistry > 2009 > 14 > 8 > 1175-1185

The mode of interaction of ataxin-3 Q36 (AT-3 Q36) with selected endogenous and exogenous metal ions, namely, Zn²⁺, Cu²⁺, Ni²⁺, and Cd²⁺, was examined. Metal-ion-induced structural changes of the protein were monitored by fluorescence as well as Fourier transform Raman spectroscopy. We found that the cations tested lead to a decrease in α-helical content and a concurrent increase in β-sheet as well...

article

Application of high pressure laser flash photolysis in studies on selected hemoprotein reactions

Małgorzata Brindell, Iwona Stawoska, Łukasz Orzeł, Przemysław Łabuz, more

BBA - Proteins and Proteomics > 2008 > 1784 > 11 > 1481-1492

This article focuses on the application of high pressure laser flash photolysis for studies on selected hemoprotein reactions with the objective to establish details of the underlying reaction mechanisms. In this context, particular attention is given to the reactions of small molecules such as dioxygen, carbon monoxide, and nitric oxide with selected hemoproteins (hemoglobin, myoglobin, neuroglobin...

article

Central Metal Determines Pharmacokinetics of Chlorophyll-Derived Xenobiotics

Małgorzata Szczygieł, Krystyna Urbańska, Patrycja Jurecka, Iwona Stawoska, more

Journal of Medicinal Chemistry > 2008 > 51 > 15 > 4412 - 4418

article

The reduction of (ImH)[trans-Ru^IIICl₄(dmso)(Im)] under physiological conditions: preferential reaction of the reduced complex with human serum albumin

Malgorzata Brindell, Iwona Stawoska, Justyna Supel, Andrzej Skoczowski, more

JBIC Journal of Biological Inorganic Chemistry > 2008 > 13 > 6 > 909-918

A systematic study of the reduction of (ImH)[trans-RuCl₄(dmso)(Im)] (NAMI-A; dmso is dimethyl sulfoxide, Im is imidazole), a promising antimetastasing agent, by l-ascorbic acid under physiological conditions is reported. Under blood plasma conditions (pH 7.4, 0.1–0.15 M NaCl , 37 °C) the rapid reduction of trans-[Ru^IIICl₄(dmso)(Im)]⁻ results in the formation of trans-[Ru^IICl₄(dmso)(Im)]²⁻ within seconds,...

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