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Target therapy for highly heterogeneous cancers represents a major clinical challenge due to the lack of recurrent therapeutic targets identified in these tumors. Herein, the authors report a tumor‐customized targeting photothermal therapy (PTT) strategy for highly heterogeneous cancers, by which 2D supramolecular self‐assembled nanodiscs are modified with tumor‐specific binding peptides identified...
Photothermal Therapy
In article number 2200179, Xuesheng Jiang, Xiaohua Yu, Zhaoming Ye, and co‐workers introduce a strategy of precise photothermal therapy for highly heterogenous cancers by a tumor‐customized 2D supramolecular nanodisc (T‐ND). By modifying Cy7‐TCF crystal with phage display derived tumor‐customized binding peptides, T‐ND shows excellent photothermal efficacy to ablate the tumor...
Asthma is characterized by chronic inflammation, and long‐term chronic inflammation leads to airway remodeling. But the potential regulatory mechanism of airway remodeling is not clearly understood, and there is still no effective way to prevent airway remodeling. Present studies have confirmed the role of microRNAs (miRNAs) in the development of disease, which is known as suppressing translation...
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