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Background and aims
Mast cells are the major effector cells in allergic disorders and many other informatory disorders. The mechanism of mast cell stabilization is not fully understood. Cumulative reports indicate that vitamin D (VitD) contributes to the homeostasis in the body. This study tests a hypothesis that VitD is required in the maintenance of the stability of mast cells.
Methods
The stability...
BackgroundB lymphocytes are an important cell population of the immune regulation; their role in the regulation of food allergy has not been fully understood yet.
ObjectiveThis study aims to investigate the role of a subpopulation of tolerogenic B cells (TolBC) in the generation of regulatory T cells (Treg) and in the suppression of food allergy‐induced intestinal inflammation in mice.
MethodsThe...
To cite this article: Chen X, Song C‐H, Liu Z‐Q, Feng B‐S, Zheng P‐Y, Li P, In SH, Tang S‐G, Yang P‐C. Intestinal epithelial cells express galectin‐9 in patients with food allergy that plays a critical role in sustaining allergic status in mouse intestine. Allergy 2011; 66: 1038–1046.
AbstractBackground and aims: Mechanisms in sustaining the allergic hypersensitivity status in the body are unclear...
To cite this article: Tian L, Li W, Wang J, Zhang Y, Zheng Y, Qi H, Guo X, Zhang Y, Ma D, Shen H, Wang Y. The CKLF1‐C19 peptide attenuates allergic lung inflammation by inhibiting CCR3‐ and CCR4‐mediated chemotaxis in a mouse model of asthma. Allergy 2011; 66: 287–297.
AbstractBackground: Human chemokine‐like factor 1 (CKLF1) is a functional ligand for human CCR4, which is highly expressed on Th2...
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