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Islet transplantation is a promising strategy for type 1 diabetes mellitus (T1DM) treatment, whereas implanted‐associated foreign body reaction (FBR) usually induces the necrosis of transplanted islets and leads to the failure of glycemic control. Benefiting from the excellent anti‐biofouling property of zwitterionic materials and their successful application in macroscopic implanted devices, microcapsules...
Bone marrow stem cells (BMSCs) engineered cartilage (BEC) is prone to endochondral ossification in a submuscular environment due to the process of vascular infiltration, which limits its application in repairing tracheal cartilage defects. Bevacizumab, an antitumor drug with pronounced antiangiogenic activity, is successfully laden into a poly(L‐lactide‐co‐caprolactone) system to prepare bevacizumab‐laden...
With the popularity of low‐dose computed tomography (LDCT) in clinical examination of the lung, the prevalence of pulmonary nodules has significantly increased, thus significantly improving the early diagnosis of lung cancer, but also potentially contributing to overtreatment. This study aims to develop a noninvasive method to assist in diagnosing the pulmonary nodules. To do so, 3798 patients are...
An accurate genotyping analysis is one of the critical prerequisites for lung cancer targeted therapy. Here, a quantitative polymerase chain reaction (qPCR)‐based mutation detection system, mutation‐selected amplification‐specific system PCR (MASS‐PCR), is developed. The specific primers and probes used in MASS‐PCR exactly match with the mutant sequence that only allows mutant gene to emit the fluorescence...
Designing rational nanostructures of metal–organic frameworks based carbon materials to promote the bifunctional catalytic activity of the oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) is highly desired but still remains a great challenge. Herein, an in situ growth method to achieve 1D structure‐controllable zeolitic imidazolate frameworks (ZIFs)/polyacrylonitrile (PAN) core/shell...
In article number 1700740, Yanyu Liang, Junhong Chen, and co‐workers report a novel copper‐based oxygen reduction electrocatalyst (Cu–N/C) facilely fabricated from copper‐doped ZIF‐8. The introduction of copper leads to not only a high‐surface‐area hierarchical structure, but also a unique hybrid coordination configuration of Cu0–Cu2+–N sites. Compared with commercial Pt/C, such highly open structures...
A transition‐metal–nitrogen/carbon (TM–N/C, TM = Fe, Co, Ni, etc.) system is a popular, nonprecious‐metal oxygen reduction reaction (ORR) electrocatalyst for fuel cell and metal–air battery applications. However, there remains a lack of comprehensive understanding about the ORR electrocatalytic mechanism on these catalysts, especially the roles of different forms of metal species on electrocatalytic...
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