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Background Information
Mammalian target of rapamycin (mTOR) complex 1 (mTORC1) is a master regulator of cell and whole‐body energy homoeostasis. REV‐ERBα is a nuclear receptor that plays an important role in metabolism. While mTORC1 activation is necessary for muscle differentiation, the role of REV‐ERBα is less clear.
Results
We studied the effect of REV‐ERBα overexpression and silencing as well...