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Caveolin‐1 is an essential component of membrane caveolae. It is an important regulator of cellular processes such as signal transduction and endocytosis. We report here, for the first time, that caveolin‐1 is a target of the K‐RAS oncogene in colon carcinogenesis. Caveolin‐1 is induced in colon cancer cells and in human colon tumor samples, in response to K‐RAS activating mutations. An activated...
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