The lipoamino acids and their oligomers provide an excellent means of enhancing peptide lipophilicity and also helping to increase the stability of the peptide and protect it from enzymatic degradation. Thyrotropin releasing hormone (TRH) and luteinizing hormone releasing hormone (LHRH) were extended on the N-terminal with one and two lipoamino acids and labelled with the 3 H-acetyl group...
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