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About this supplement These abstracts have been published as part of BMC Neuroscience Volume 18 Supplement 1, 2017. The full contents of the supplement are available online at https://bmcneurosci.biomedcentral.com/articles/supplements/volume-18-supplement-1 . Please note that this is part 3 of 3.
An important aspect of homology modeling and protein design algorithms is the correct positioning of protein side chains on a fixed backbone. Homology modeling methods are necessary to complement large scale structural genomics projects. Recently it has been shown that in automatic protein design it is of the uttermost importance to find the global solution to the side chain positioning problem [1]...
Background One of the most well described cellular processes is the cell cycle, governing cell division. Mathematical models of this gene-protein network are therefore a good test case for assessing to what extent we can dissect the relationship between model parameters and system dynamics. Here we combine two strategies to enable an exploration of parameter space in relation to model output. A simplified,...
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