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US-amerikanische Protagonisten der „Public Health Genetics“ beschreiben die Genetik als ein Instrument, das sich perfekt mit den Zielsetzungen von Public Health vereinen lässt. So sieht beispielsweise der amerikanische Humangenetiker Gilbert Omenn (2000a: 25, 2000b: 1) mit der „Hochzeit“ von Genetik und Public Health ein „goldenes Zeitalter“ für die Public Health Forschung anbrechen. Diese Hoffnung...
Thiopurine drug metabolism is a quintessential case of pharmacogenetics. A wealth of experimental and clinical data on polymorphisms in the thiopurine metabolizing enzyme thiopurine methyl transferase (TPMT) has been generated in the past decade. Pharmacogenetic testing prior to thiopurine treatment is already being practiced to some extent in the clinical context, and it is likely that it will be...
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