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Ein 3-jähriger Junge entwickelte innerhalb weniger Tage eine generalisierte bullöse Dermatose, die klinisch einer chronisch bullösen Dermatose des Kindesalters (CBDC) entsprach. Die Diagnose wurde histologisch bestätigt und durch immunmorphologische und biochemische Untersuchungen verifiziert. In der direkten Immunfluoreszenz (IF) periläsionaler Haut fanden sich in vivo gebundene IgA-Autoantikörper...
Although the overall efficacy of high dose intravenous immunoglobulin (hlVIG) in the treatment of dermatomyositis (DM) has been well documented, no clinical and/or serological parameters predicting a favorable treatment response have been defined. In the present trial, 8 patients suffering from DM and 3 patients with polymyositis/overlap syndrome (POS) were treated with monthly pulses of hlVIG (2g/KG...
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